BDBM694830 3-(4-((R)-4,4-difluoro-2-methylpiperidin-1-yl)-7-(1H-pyrazol-3-yl)imidazo[1,5-b]pyridazin-2-yl)-8-oxa-3-azabicyclo[3.2.1]octane, and 3-(4-((S)-4,4-difluoro-2-methylpiperidin-1-yl)-7-(1H-pyrazol-3-yl)imidazo[1,5-b]pyridazin-2-yl)-8-oxa-3-azabicyclo[3.2.1]octane::US20240294550, Example 31::US20240294550, Example 32

SMILES C[C@H]1CC(F)(F)CCN1c1cc(nn2c(ncc12)-c1cc[nH]n1)N1CC2CCC(C1)O2

InChI Key InChIKey=HPMGRWUCQNFIKQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 694830   

TargetSerine/threonine-protein kinase ATR(Human)
Littdd Medicines

US Patent
LigandPNGBDBM694830(US20240294550, Example 31 | 3-(4-((R)-4,4-difluoro...)
Affinity DataIC50: 3.90nMAssay Description:This experiment adopted Homogeneous time-resolved fluorescence technology (HTRF ) of Cisbio Company for assay.Experiment method: buffers were prepare...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase ATR(Human)
Littdd Medicines

US Patent
LigandPNGBDBM694830(US20240294550, Example 31 | 3-(4-((R)-4,4-difluoro...)
Affinity DataIC50: 5.60nMAssay Description:This experiment adopted Homogeneous time-resolved fluorescence technology (HTRF ) of Cisbio Company for assay.Experiment method: buffers were prepare...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent