BDBM695538 US12084416, Example 139

SMILES O=C(Nc1c2CCCc2cc2CCCc12)[N-]S(=O)(=O)\C=C\[C@H]1CCCN1C1CCSCC1

InChI Key InChIKey=YPMLXTSZWOTFEF-UHFFFAOYSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 695538   

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandPNGBDBM695538(US12084416, Example 139)
Affinity DataIC50: 21nMAssay Description:THP1 monocytes were differentiated with PMA (100 ng/mL) and incubated at 37 deg C. for 20 hrs in presence of 5% CO2. 2×105 differentiated cells were ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent