BDBM695780 US12084420, Compound 140a

SMILES C[C@H]1CC[C@]2(CN(C(=O)c3cccc(c3)S(=O)(=O)NC(C)(C)C)c3ccc(NS(C)(=O)=O)cc23)CC1

InChI Key

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 695780   

TargetKinesin-like protein KIF18A(Human)
Volastra Therapeutics

US Patent
LigandPNGBDBM695780(US12084420, Compound 140a)
Affinity DataKi:  0.5nMAssay Description:Table 10: Compound binding kinetics parameters (kon and koff) were determined by the method of global progress curve analysis (GPCA). KIF18A (0.25 nM...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent