BDBM695810 3-((8-Chloro-1-(2,6-dichloro-4-(2-hydroxy-2-methylpropoxy)phenyl)-2-methyl-4-oxo-1,4-dihydro-1,6-naphthyridin-5-yl)oxy)-N-methylpropanamide ::US12084442, Example 3

SMILES CNC(=O)CCOc1ncc(Cl)c2n(c(C)cc(=O)c12)-c1c(Cl)cc(OCC(C)(C)O)cc1Cl

InChI Key InChIKey=ZXQBGOFLQKVHTQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 695810   

LigandPNGBDBM695810(US12084442, Example 3 | 3-((8-Chloro-1-(2,6-dichlo...)
Affinity DataIC50: 220nMAssay Description:The GIRK1/4 activity of a compound according to the present invention was assessed by the following in vitro method.Buffers:a. External buffer: 10 mM...More data for this Ligand-Target Pair
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Date in BDB:
1/6/2025
Entry Details
US Patent