BDBM695811 2-((8-Chloro-1-(2,6-dichloro-4-(2-hydroxy-2-methylpropoxy)phenyl)-2-methyl-4-oxo-1,4-dihydro-1,6-naphthyridin-5-yl)oxy)-N-methylacetamide ::US12084442, Example 4

SMILES CNC(=O)COc1ncc(Cl)c2n(c(C)cc(=O)c12)-c1c(Cl)cc(OCC(C)(C)O)cc1Cl

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 695811   

LigandPNGBDBM695811(US12084442, Example 4 | 2-((8-Chloro-1-(2,6-dichlo...)
Affinity DataIC50: 160nMAssay Description:The GIRK1/4 activity of a compound according to the present invention was assessed by the following in vitro method.Buffers:a. External buffer: 10 mM...More data for this Ligand-Target Pair
Ligand InfoSimilars
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Date in BDB:
1/6/2025
Entry Details
US Patent