BDBM695829 8-Chloro-1-(2,6-dichloro-4-(2-hydroxy-2-methylpropoxy)phenyl)-2-methyl-5-(3-(methylsulfonyl)propyl)-1,6-naphthyridin-4(1H)-one ::US12084442, Example 22

SMILES Cc1cc(=O)c2c(CCCS(C)(=O)=O)ncc(Cl)c2n1-c1c(Cl)cc(OCC(C)(C)O)cc1Cl

InChI Key InChIKey=CMBMXTIBBVBBQP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 695829   

LigandPNGBDBM695829(US12084442, Example 22 | 8-Chloro-1-(2,6-dichloro-...)
Affinity DataIC50: 190nMAssay Description:The GIRK1/4 activity of a compound according to the present invention was assessed by the following in vitro method.Buffers:a. External buffer: 10 mM...More data for this Ligand-Target Pair
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Date in BDB:
1/6/2025
Entry Details
US Patent