BDBM696013 6-(1H-indazol-6-yl)-N2-[1-methyl-1-[6-(trifluoromethyl)-2-pyridyl]ethyl]-1,3,5-tr iazine-2,4-diamine hydrochloride::US20240300936, Example 4

SMILES CC(C)(Nc1nc(N)nc(n1)-c1ccc2cn[nH]c2c1)c1cccc(n1)C(F)(F)F

InChI Key InChIKey=IMPFGHRZJLQSFM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 696013   

TargetSerine/threonine-protein kinase greatwall(Human)
Avelos Therapeutics

US Patent
LigandPNGBDBM696013(US20240300936, Example 4 | 6-(1H-indazol-6-yl)-N2-...)
Affinity DataIC50: 1.95nMAssay Description:Wild-type human MASTL (0.5 nM) was incubated in assay buffer (30 mM HEPES, 100 mM NaCl, 0.5 mM EGTA, 10 mM MgCl2, 0.01% Tween-20, 0.5 mM TCEP, pH 7.5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/8/2025
Entry Details
US Patent