BDBM696671 6-(1-((1- cyanocyclopropyl)methyl)-1H- pyrazol-4-yl)-N-(5-(4-(2- hydroxypropan-2-yl)-2- azabicyclo[2.1.1]hexan-2-yl)- 2(trifluoromethyl)pyridin-3- yl)picolinamide::US20240308980, Ex-1.36

SMILES CC(C)(O)C16CC(C1)N(c5cnc(C(F)(F)F)c(NC(=O)c4cccc(c3cnn(CC2(C#N)CC2)c3)n4)c5)C6

InChI Key InChIKey=RAOCTROTLLJFDW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 696671   

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM696671(6-(1-((1- cyanocyclopropyl)methyl)-1H- pyrazol-4-y...)
Affinity DataIC50: 80nMAssay Description:Compound potency against LRRK2 kinase activity was determined using LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA) using a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2025
Entry Details
US Patent