BDBM696677 US20240308985, Compound 127

SMILES Cc1cc(C2CC3(C2)CN(C3)C(=O)c2c(F)ccc(O)c2F)n(n1)-c1ccccc1C

InChI Key InChIKey=HTDSNNCWQUUVRQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 696677   

TargetMonoglyceride lipase [2-303](Homo sapiens (Human))
Psy Therapeutics

US Patent
LigandPNGBDBM696677(US20240308985, Compound 127 | US20250170100, Compo...)
Affinity DataIC50: 3.05E+3nMAssay Description:MAGL Inhibition was measured by the following assay. Monoacylglycerol Lipase (MAGL) inhibition was measured using recombinant MAGL enzyme (aa 2-303 R...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
US Patent

TargetFatty-acid amide hydrolase 1(Human)
Psy Therapeutics

US Patent
LigandPNGBDBM696677(US20240308985, Compound 127 | US20250170100, Compo...)
Affinity DataIC50: 1.00E+4nMAssay Description:MAGL inhibitor compounds were also counter-screened for FAAH inhibition potency using the following assay. Assessment of FAAH inhibition was performe...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
US Patent

TargetFatty-acid amide hydrolase 1(Human)
Psy Therapeutics

US Patent
LigandPNGBDBM696677(US20240308985, Compound 127 | US20250170100, Compo...)
Affinity DataIC50: 1.00E+4nMAssay Description:MAGL inhibitor compounds were also counter-screened for FAAH inhibition potency using the following assay. Assessment of FAAH inhibition was performe...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/22/2025
Entry Details
US Patent