BDBM696765 N-(5-methyl-2- morpholinopyridin-4-yl)-6-(1H- pyrazol-4-yl)picolinamide::US20240308980, Ex-5.12

SMILES Cc1cnc(cc1NC(=O)c1cccc(n1)-c1cn[nH]c1)N1CCOCC1

InChI Key InChIKey=BUTRDBIUYHDFDC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 696765   

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM696765(N-(5-methyl-2- morpholinopyridin-4-yl)-6-(1H- pyra...)
Affinity DataIC50: 2.35E+3nMAssay Description:Compound potency against LRRK2 kinase activity was determined using LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA) using a...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
US Patent