BDBM696776 N-(6-((3S,4r,5R)-4-hydroxy- 3,4,5-trimethylpiperidin-1-yl)- 2-methylpyrimidin-4-yl)-6-(1- methyl-1H-pyrazol-4- yl)picolinamide::US20240308980, Ex-6.11

SMILES C[C@H]1CN(C[C@@H](C)[C@]1(C)O)c1cc(NC(=O)c2cccc(n2)-c2cnn(C)c2)nc(C)n1

InChI Key InChIKey=RYJTZZOMIJHPCK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 696776   

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM696776(N-(6-((3S,4r,5R)-4-hydroxy- 3,4,5-trimethylpiperid...)
Affinity DataIC50: 2.01E+3nMAssay Description:Compound potency against LRRK2 kinase activity was determined using LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA) using a...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
US Patent