BDBM696955 US20240308995, Example 1-153::US20240308995, Example 1-35

SMILES COc1cc(O[C@@H]2CC[C@H](C)N(Cc3sc(NC(C)=O)nc3F)C2)ncn1

InChI Key InChIKey=ZIFIOXPFRCXXBI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 696955   

TargetProtein O-GlcNAcase(Human)
Biogen Ma

US Patent
LigandPNGBDBM696955(US20240308995, Example 1-35 | US20240308995, Examp...)
Affinity DataIC50: 1nMAssay Description:Recombinant full length human OGA enzyme was purchased from Origene. 4-MUGlcNAc substrate was purchased from Sigma. All other reagents were purchased...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Biogen Ma

US Patent
LigandPNGBDBM696955(US20240308995, Example 1-35 | US20240308995, Examp...)
Affinity DataIC50: 1nMAssay Description:Recombinant full length human OGA enzyme was purchased from Origene. 4-MUGlcNAc substrate was purchased from Sigma. All other reagents were purchased...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
US Patent