BDBM697186 1-(1- oxaspiro[4.4] nonan-3-yl)-3- [(2-pyrazol-1- ylpyridin-4- yl)methyl]urea::US20240316020, Example 1

SMILES O=C(NCc1ccnc(c1)-n1cccn1)NC1COC2(CCCC2)C1

InChI Key InChIKey=DHHVULWDNAXLMR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 697186   

LigandPNGBDBM697186(US20240316020, Example 1 | 1-(1- oxaspiro[4.4] non...)
Affinity DataEC50:  3.63E+3nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent