BDBM697187 1-(6- oxaspiro[4.5] decan-9-yl)-3-[(2- pyrazol-1- ylpyridin-4- yl)methyl]urea::US20240316020, Example 2

SMILES O=C(NCc1ccnc(c1)-n1cccn1)NC1CCOC2(CCCC2)C1

InChI Key InChIKey=GEMHEOUZNIBZFB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 697187   

LigandPNGBDBM697187(US20240316020, Example 2 | 1-(6- oxaspiro[4.5] dec...)
Affinity DataEC50:  8.49E+3nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
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Date in BDB:
1/28/2025
Entry Details
US Patent