BDBM697194 1-[[2-(1,1- difluoroethyl) pyridin-4-yl]methyl]- 3- spiro[3.3]heptan- 2-ylurea::US20240316020, Example 9

SMILES CC(F)(F)c1cc(CNC(=O)NC2CC3(CCC3)C2)ccn1

InChI Key InChIKey=YXFKFGHQCHBASC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 697194   

LigandPNGBDBM697194(US20240316020, Example 9 | 1-[[2-(1,1- difluoroeth...)
Affinity DataEC50:  190nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent