BDBM697199 1-[[2- (difluoromethoxy) pyridin-4- yl]methyl]-3-(6- oxaspiro[4.5] decan-9-yl)urea::BDBM697202::US20240316020, Example 14

SMILES FC(F)Oc1cc(CNC(=O)NC2CCOC3(CCCC3)C2)ccn1

InChI Key InChIKey=SNLDAXXNTJQMCA-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 697199   

LigandPNGBDBM697199(US20240316020, Example 14 | BDBM697202 | 1-[[2- (d...)
Affinity DataEC50:  260nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandPNGBDBM697199(US20240316020, Example 14 | BDBM697202 | 1-[[2- (d...)
Affinity DataEC50:  260nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandPNGBDBM697199(US20240316020, Example 14 | BDBM697202 | 1-[[2- (d...)
Affinity DataEC50:  340nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandPNGBDBM697199(US20240316020, Example 14 | BDBM697202 | 1-[[2- (d...)
Affinity DataEC50:  340nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandPNGBDBM697199(US20240316020, Example 14 | BDBM697202 | 1-[[2- (d...)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandPNGBDBM697199(US20240316020, Example 14 | BDBM697202 | 1-[[2- (d...)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent