BDBM698086 US20240317714, Example A78

SMILES CN1CCC(CC1)n1cc(Oc2nc(cnc2N)-c2cc(cc(c2)C2(O)COC2)N2CC3(COC3)C2)cn1

InChI Key InChIKey=BQWPRYZZSGQBAQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 698086   

LigandPNGBDBM698086(US20240317714, Example A78 | US20250236610, Exampl...)
Affinity DataIC50: 5.5nMAssay Description:Compounds disclosed herein were tested for inhibition of HPK1 kinase (aa1-346, Life Technologies) activity in assays based on the time-resolved fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM698086(US20240317714, Example A78 | US20250236610, Exampl...)
Affinity DataIC50: 5.5nMAssay Description:Compounds disclosed herein were tested for inhibition of HPK1 kinase (aal-346. Life Technologies) activity in assays based on the time-resolved fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent