BDBM698790 (2-((1- ((dimethylamino)methyl)cyclopropyl) methoxy)-4-thiomorpholino-5,7- dihydro-6H-pyrrolo[3,4-d]pyrimidin- 6-yl)(3-hydroxy-8-iodonaphthalen-1- yl)methanone::US20240317759, Example 2

SMILES N#Cc1cc(Cl)cc2c1CC(Nc1ncc(C(=O)N3CCC34COC4)cn1)C2

InChI Key InChIKey=GBIHMPJZUYNIIJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 698790   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 698790BDBM698790(2-((5-(6-oxa-1- azaspiro[3.3]heptane-1- carbonyl)p...)
Affinity DataIC50: 20.8nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2026
Entry Details
US Patent