BDBM698795 (2-((6-chloro-4-(prop- l-yn-1-yl)-2,3-dihydro- lH-inden-2- yl)amino)pyrimidin-5- yl)(6-oxa-1- azaspiro[3.3]heplan-l - yl)methanone::US12600712, Example 7

SMILES CC#Cc1cc(Cl)cc2c1CC(Nc1ncc(C(=O)N3CCC34COC4)cn1)C2

InChI Key InChIKey=XPZUNAZJHRDONN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 698795   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 698795BDBM698795((2-((6-chloro-4-(prop- l-yn-1-yl)-2,3-dihydro- lH-...)
Affinity DataIC50: 23.7nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2026
Entry Details
US Patent