BDBM698799 US12600712, Example 11

SMILES N#Cc1cc(Cl)cc2c1C[C@@H](Nc1ncc(C(=O)N3CCC34COC4)cn1)C2

InChI Key InChIKey=IEGMVFCMBVSNLK-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 698799   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 698799BDBM698799(US12600712, Example 11)
Affinity DataIC50: 7.40nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2026
Entry Details
US Patent
PDB3D3D Structure (crystal)