BDBM698800 (S)-6-chloro-2-((5-(2,2- dimethylazetidine-1- carbonyl)pyrimidin-2- yl)amino)-2.3-dihydro- 1H-indene-4- carbonitrile::US12600712, Example 12

SMILES CC1(C)CCN1C(=O)c1cnc(N[C@H]2Cc3cc(Cl)cc(C#N)c3C2)nc1

InChI Key InChIKey=CDBZYFBLLSMAKW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 698800   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 698800BDBM698800((S)-6-chloro-2-((5-(2,2- dimethylazetidine-1- carb...)
Affinity DataIC50: 6.5nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2026
Entry Details
US Patent