BDBM698801 (S)-6-chloro-2-((5-(6,6- difluoro-1- azaspiro[3.3]heptane-1- carbonyl)pyrimidin-2- yl)amino)-2,3-dihydro- 1H-indene-4- carbonitrile::US12600712, Example 13

SMILES N#Cc1cc(Cl)cc2c1C[C@@H](Nc1ncc(C(=O)N3CCC34CC(F)(F)C4)cn1)C2

InChI Key InChIKey=ATNASTPUZYCYEE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 698801   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 698801BDBM698801((S)-6-chloro-2-((5-(6,6- difluoro-1- azaspiro[3.3]...)
Affinity DataIC50: 3nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2026
Entry Details
US Patent