BDBM698819 US12600714, Compound 503

SMILES CCc1cc(Nc2nc(NC3CC4(COC4)C3)c(-c3cc[nH]n3)nc2C(N)=O)ccc1N1CCC(N2CCN(C)CC2)CC1

InChI Key InChIKey=QAYIZAUNJZBCET-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 698819   

TargetEpidermal growth factor receptor(Human)
Wigen Biomedicine Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 698819BDBM698819(US12600714, Compound 503)
Affinity DataIC50: 10.2nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2026
Entry Details
US Patent