BDBM698871 US20260103453, Example 1

SMILES C=CC(=O)N(C)CC#Cc1c(N)ncnc1-c1cc(F)cc(NC(=O)c2ccc(C(C)C)cc2F)c1C

InChI Key InChIKey=AGNHIHJMIQZVTG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 698871   

TargetTyrosine-protein kinase BTK(Human)
Hanmi Pharm. Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 698871BDBM698871(US20260103453, Example 1)
Affinity DataIC50: 1.70nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2026
Entry Details
US Patent