BDBM698875 US20260103453, Example 4

SMILES C=CC(=O)N(C)CC#Cc1c(N)ncnc1-c1cc(F)cc(N2CCc3cc(C4CC4)cc(F)c3C2=O)c1C

InChI Key InChIKey=KSGDOQWVUVGXCT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 698875   

TargetTyrosine-protein kinase BTK(Human)
Hanmi Pharm. Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 698875BDBM698875(US20260103453, Example 4)
Affinity DataIC50: 5.30nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2026
Entry Details
US Patent