BDBM698906 (2-(((2S,7aR)-2-fluorotetrahydro- 1H-pyrrolizin-7a(5H)-yl)methoxy)- 4-((R)-3-hydroxy-3- methylpiperidin-1-yl)-5,7-dihydro- 6H-pyrrolo[3,4-d]pyrimidin-6-yl)(3- hydroxy-8-iodonaphthalen-1- yl)methanone::BDBM698907::US20240317759, Example 115

SMILES O=C1c2sc(-c3ccc(N4CCCCC4)nc3F)nc2CCN1c1ccnc(F)c1

InChI Key InChIKey=YXLUOVNHMQIJHS-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 698906   

TargetTAR DNA-binding protein 43(Human)
AC Immune

US Patent
LigandChemical structure of BindingDB Monomer ID 698906BDBM698906(US20260103474, Example 23)
Affinity DataKi: >1.00E+3nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2026
Entry Details
US Patent