BDBM699017 US20240327389, Compound 1018

SMILES Cc1c(COc2cc(OCc3cncc(c3)C#N)c(CNC3CCOC3=O)cc2Cl)cccc1-c1cccc(COc2cc(OCc3cncc(c3)C#N)c(CNC3CCOC3=O)cc2Cl)c1C

InChI Key InChIKey=ORTHUWFJNARPQI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 699017   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM699017(US20240327389, Compound 1018)
Affinity DataIC50: 15nMAssay Description:TRF assay buffer consisting of dPBS supplemented with 0.1% (w/v) bovine serum albumin and 0.05% (v/v) Tween-20. For the PD-1-Ig/PD-L1-His binding ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent