BDBM699125 US20240327418, Example LEE8

SMILES Nc1ccccc1NC(=O)CCCCCCCNC(=O)\C=C\c1cccnc1

InChI Key InChIKey=QMBIRBVZKDZJJI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 699125   

TargetHistone deacetylase 3(Human)
Ocean University of China

US Patent
LigandPNGBDBM699125(US20240327418, Example LEE8)
Affinity DataIC50: 26.4nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Ocean University of China

US Patent
LigandPNGBDBM699125(US20240327418, Example LEE8)
Affinity DataIC50: 147nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
Ocean University of China

US Patent
LigandPNGBDBM699125(US20240327418, Example LEE8)
Affinity DataIC50: 321nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent