BDBM699132 US20240327418, Example LEE10

SMILES CCCNNC(=O)CCCCCCCn1cc(nn1)-c1cccnc1

InChI Key InChIKey=ULYVQURTWGHWFS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 699132   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM699132(US20240327418, Example LEE10)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of C-terminal His-tagged human HDAC3 (1 to 428 residues)/N-terminal GST tagged human NCOR2 (395 to 489 residues) expressed in baculovirus-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Ocean University of China

US Patent
LigandPNGBDBM699132(US20240327418, Example LEE10)
Affinity DataIC50: 5.43nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM699132(US20240327418, Example LEE10)
Affinity DataIC50: 57nMAssay Description:Inhibition of C-terminal 6XHis-tagged/FLAG-tagged full length human recombinant HDAC1 (1 to 482 residues) expressed in baculovirus-infected Sf9 cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM699132(US20240327418, Example LEE10)
Affinity DataIC50: 57.4nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
Ocean University of China

US Patent
LigandPNGBDBM699132(US20240327418, Example LEE10)
Affinity DataIC50: 150nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
Ocean University of China

US Patent
LigandPNGBDBM699132(US20240327418, Example LEE10)
Affinity DataIC50: 150nMAssay Description:Inhibition of C-terminal 6XHis-tagged full length human recombinant HDAC2 (1 to 488 residues) expressed in baculovirus-infected Sf9 cells using Boc-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM699132(US20240327418, Example LEE10)
Affinity DataIC50: 900nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant NAMPT (2 to 491 residues) expressed in Escherichia coli expression system incubated for 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed