BDBM69935 3-(2-besylacetyl)coumarin::3-[2-(benzenesulfonyl)-1-oxoethyl]-1-benzopyran-2-one::3-[2-(benzenesulfonyl)acetyl]chromen-2-one::3-[2-(phenylsulfonyl)ethanoyl]chromen-2-one::MLS001028611::SMR000634135::cid_688785

SMILES O=C(CS(=O)(=O)c1ccccc1)c1cc2ccccc2oc1=O

InChI Key InChIKey=SOAMCCSEKSKSMW-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 69935   

TargetCarbonic anhydrase 9(Human)
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM69935(3-[2-(phenylsulfonyl)ethanoyl]chromen-2-one | 3-[2...)
Affinity DataKi:  41nMAssay Description:Inhibition of human CA9 preincubated for 6 hrs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM69935(3-[2-(phenylsulfonyl)ethanoyl]chromen-2-one | 3-[2...)
Affinity DataKi:  60nMAssay Description:Inhibition of human CA12 preincubated for 6 hrs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM69935(3-[2-(phenylsulfonyl)ethanoyl]chromen-2-one | 3-[2...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human CA2 preincubated for 6 hrs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM69935(3-[2-(phenylsulfonyl)ethanoyl]chromen-2-one | 3-[2...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human CA1 preincubated for 6 hrs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM69935(3-[2-(phenylsulfonyl)ethanoyl]chromen-2-one | 3-[2...)
Affinity DataEC50: >3.00E+5nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay