BDBM699568 BDBM699584::US12110299, Example 81

SMILES C[C@H](C(=O)Nc1ncc(s1)C(F)(F)F)c1cccc(c1)-c1cnc(NC(=O)\C=C\CN(C)C)cn1

InChI Key InChIKey=XUJVLDKMRYFEDL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 699568   

TargetCyclin-dependent kinase 7(Human)
Yungjin Pharm.

US Patent
LigandPNGBDBM699568(BDBM699584 | US12110299, Example 81)
Affinity DataIC50: 6.40nMAssay Description:Representative compounds of the present invention were assayed in vitro for CDK7 kinase-inhibitory activities using ADP-Glo platform. In detail, CDK7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Yungjin Pharm.

US Patent
LigandPNGBDBM699568(BDBM699584 | US12110299, Example 81)
Affinity DataIC50: 8nMAssay Description:Representative compounds of the present invention were assayed in vitro for CDK7 kinase-inhibitory activities using ADP-Glo platform. In detail, CDK7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2025
Entry Details
US Patent