BDBM699682 US12110299, Example 115

SMILES C[C@H](C(=O)Nc1ncc(s1)C(F)(F)F)c1cccc(c1)-c1cnc(NC(=O)\C=C\CN2CC[C@@H](F)C2)cn1

InChI Key InChIKey=FFXGZCNNYHMJIW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 699682   

TargetCyclin-dependent kinase 7(Human)
Yungjin Pharm.

US Patent
LigandPNGBDBM699682(US12110299, Example 115)
Affinity DataIC50: 17nMAssay Description:Representative compounds of the present invention were assayed in vitro for CDK7 kinase-inhibitory activities using ADP-Glo platform. In detail, CDK7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2025
Entry Details
US Patent