BDBM699816 US20240335427, Compound 46

SMILES O=C(NCC1CN(C1)C#N)c1nc2ccccc2s1

InChI Key InChIKey=CRRPSWYSKMFWPL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 699816   

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699816(US20240335427, Compound 46)
Affinity DataIC50: 1.13E+4nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699816(US20240335427, Compound 46)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent