BDBM700288 1-Methyl-3-[2-[[4-[1-methyl-4-(4-pyridyl)pyrazol-3-yl]phenoxy]methyl]-4-quinolyl]urea::US20240336591, Example 35

SMILES CNC(=O)Nc1cc(COc2ccc(cc2)-c2nn(C)cc2-c2ccncc2)nc2ccccc12

InChI Key InChIKey=DSBCMABHNGBNFA-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 700288   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform 2(Human)
Benevolentai Cambridge

US Patent

LigandBDBM700288(1-Methyl-3-[2-[[4-[1-methyl-4-(4-pyridyl)pyrazol-3...)Copy SMILESCopy InChI

Affinity DataIC50: 0.214nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/10/2025
Entry Details
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