BDBM700325 Preparation of trans-1-(6-((3,4-difluorophenyl)amino)pyrimidin-4-yl)-4-(3,4-dihydroisoquinolin-2(1H)-yl)piperidin-3-ol::US20240336593, Example 78

SMILES O[C@H]1CN(CC[C@@H]1N1CCc2ccccc2C1)c1cc(Nc2ccc(F)c(F)c2)ncn1

InChI Key InChIKey=QLMSBGBBRIGXIO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 700325   

TargetProtein arginine N-methyltransferase 5(Human)
Lnnovstonetherapeutics

US Patent
LigandPNGBDBM700325(US20240336593, Example 78 | Preparation of trans-1...)
Affinity DataIC50: 100nMAssay Description:Test method: A 1× enzyme reaction buffer (10 mM Tris 8.0 (Sigma, Cat. No. T2694-1L), 0.01% Tween-20 (Sigma, Cat. No. P2287-100 ML), 1 mM DTT (Sigma, ...More data for this Ligand-Target Pair
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Date in BDB:
2/10/2025
Entry Details
US Patent