BDBM700401 US20240336610, Example 7::US20240336610, GDI-007

SMILES CC(=O)N[C@H](C(=O)N1C[C@H]2[C@@H]([C@H]1C(=O)NC(C#N)c1cncc(c1)C(F)(F)F)C2(C)C)C(C)(C)C

InChI Key InChIKey=PGPTUVHKEZHKMO-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 700401   

TargetReplicase polyprotein 1a(2019-nCoV)
The Global Health Drug Discovery Institute

US Patent
LigandPNGBDBM700401(US20240336610, Example 7 | US20240336610, GDI-007)
Affinity DataIC50: 170nMAssay Description:An inhibition test was conducted using 200 nM recombinant SARS-CoV-2 main protease and 15 μM fluorescent substrate (Dabcyl-TSAVL QSGFRK-Glu (EDA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
The Global Health Drug Discovery Institute

US Patent
LigandPNGBDBM700401(US20240336610, Example 7 | US20240336610, GDI-007)
Affinity DataEC50:  512nMAssay Description:An inhibition test was conducted using 200 nM recombinant SARS-CoV-2 main protease and 15 μM fluorescent substrate (Dabcyl-TSAVL QSGFRK-Glu (EDA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent