BDBM700471 BDBM700472::US20240336629, Compound 23A

SMILES CCN1C(=O)[C@@H]2CN(CCN2c2ncc(Br)cc12)C(=O)CCOC[C@H](C)Nc1cn[nH]c(=O)c1C(F)(F)F

InChI Key InChIKey=WTGRFEDOZJKCTI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 700471   

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM700471(US20240336629, Compound 23A | BDBM700472)
Affinity DataIC50: 0.804nMAssay Description:(1) Each compound to be tested was prepared using gradient dilution method with DMSO and water to obtain a solution with the concentration of 50 nM, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM700471(US20240336629, Compound 23A | BDBM700472)
Affinity DataIC50: 0.863nMAssay Description:(1) Each compound to be tested was prepared using gradient dilution method with DMSO and water to obtain a solution with the concentration of 50 nM, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent