BDBM700482 US20240336629, Compound 29A

SMILES COC[C@@H](COCCC(=O)N1CCN2[C@@H](C1)C(=O)N(C)c1cc(cnc21)C(F)(F)F)Nc1cnn(Cc2ccc(OC)cc2)c(=O)c1C(F)(F)F

InChI Key InChIKey=YWHSZJGSHYXPLY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 700482   

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM700482(US20240336629, Compound 29A)
Affinity DataIC50: 0.861nMAssay Description:(1) Each compound to be tested was prepared using gradient dilution method with DMSO and water to obtain a solution with the concentration of 50 nM, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent