BDBM700505 US20240336629, Compound 49A

SMILES C[C@@H](COCCC(=O)N1CCn2c(C1)nc1cc(cnc21)C(F)(F)F)Oc1cn[nH]c(=O)c1C(F)(F)F

InChI Key InChIKey=VFMIYMXHIVDKHZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 700505   

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM700505(US20240336629, Compound 49A)
Affinity DataIC50: 0.967nMAssay Description:(1) Each compound to be tested was prepared using gradient dilution method with DMSO and water to obtain a solution with the concentration of 50 nM, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent