BDBM700508 US20240336629, Compound 53

SMILES C[C@@H](COCCC(=O)N1CCN2C(COc3cc(cnc23)C(F)(F)F)C1)Nc1cn[nH]c(=O)c1C(F)(F)F

InChI Key InChIKey=HYSXVIKHLSSMJN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 700508   

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Guizhou University

Curated by ChEMBL
LigandPNGBDBM700508(US20240336629, Compound 53)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of PARP7 (unknown origin) using histone as substrate incubated for 1 hr by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Guizhou University

Curated by ChEMBL
LigandPNGBDBM700508(US20240336629, Compound 53)
Affinity DataIC50: 2.13nMAssay Description:(1) Each compound to be tested was prepared using gradient dilution method with DMSO and water to obtain a solution with the concentration of 50 nM, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent