BDBM700540 US20240336629, Compound 67A

SMILES COC[C@@H](COCCC(=O)N1CCN2[C@H](C1)CCOc1cc(Cl)cnc21)Nc1cn[nH]c(=O)c1C(F)(F)F

InChI Key InChIKey=WXEBPDOZLIXZKP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 700540   

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Hubei Polytechnic University

Curated by ChEMBL
LigandPNGBDBM700540(US20240336629, Compound 67A)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PARP7 (unknown origin) incubated for 1 hr by chemiluminescence based microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Hubei Polytechnic University

Curated by ChEMBL
LigandPNGBDBM700540(US20240336629, Compound 67A)
Affinity DataIC50: 1.66nMAssay Description:(1) Each compound to be tested was prepared using gradient dilution method with DMSO and water to obtain a solution with the concentration of 50 nM, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent