BDBM700543 US20240336629, Compound 68B

SMILES COC[C@@H](COCCC(=O)N1CCN2[C@H](C1)CCOc1cc(cnc21)C(F)(F)F)Nc1cn[nH]c(=O)c1C(F)(F)F

InChI Key InChIKey=XZJYBMADQLZNRL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 700543   

LigandPNGBDBM700543(US20240336629, Compound 68B)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PARP7 (unknown origin) incubated for 1 hr by chemiluminescence based microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM700543(US20240336629, Compound 68B)
Affinity DataIC50: 4.29nMAssay Description:(1) Each compound to be tested was prepared using gradient dilution method with DMSO and water to obtain a solution with the concentration of 50 nM, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandPNGBDBM700543(US20240336629, Compound 68B)
Affinity DataIC50: 2.32E+3nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details