BDBM700576 BDBM700577::US20240336629, Compound 84A

SMILES CCN1[C@@H](CNC(=O)CCOC[C@@H](C)Oc2cn[nH]c(=O)c2C(F)(F)F)CCOc2cc(Cl)cnc12

InChI Key InChIKey=OCPMKYXBYBLMKN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 700576   

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM700576(BDBM700577 | US20240336629, Compound 84A)
Affinity DataIC50: 1.01nMAssay Description:(1) Each compound to be tested was prepared using gradient dilution method with DMSO and water to obtain a solution with the concentration of 50 nM, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM700576(BDBM700577 | US20240336629, Compound 84A)
Affinity DataIC50: 4.01nMAssay Description:(1) Each compound to be tested was prepared using gradient dilution method with DMSO and water to obtain a solution with the concentration of 50 nM, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent