BDBM700589 US20240336629, Compound 90B

SMILES FC(F)(F)c1c(cn[nH]c1=O)N1CC[C@H]1COCCC(=O)N1CCN2[C@H](C1)CCOc1cc(Cl)cnc21

InChI Key InChIKey=YSVWRWHSYZIFDS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 700589   

LigandPNGBDBM700589(US20240336629, Compound 90B)
Affinity DataIC50: 0.110nMAssay Description:Inhibition of PARP7 (unknown origin) incubated for 1 hr by chemiluminescence based microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM700589(US20240336629, Compound 90B)
Affinity DataIC50: 0.792nMAssay Description:(1) Each compound to be tested was prepared using gradient dilution method with DMSO and water to obtain a solution with the concentration of 50 nM, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandPNGBDBM700589(US20240336629, Compound 90B)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PARP14 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM700589(US20240336629, Compound 90B)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PARP12 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM700589(US20240336629, Compound 90B)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PARP11 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM700589(US20240336629, Compound 90B)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM700589(US20240336629, Compound 90B)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed