BDBM700974 N-(5-amino-4-methoxy-2- (methyl(2- morpholinoethyl)amino)phenyl) acrylamide::US20240343694, Example 63

SMILES C=CC(=O)Nc1cc(N)c(OC)cc1N(C)CCN2CCOCC2

InChI Key InChIKey=RWPZPXNEYXGGCD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 700974   

TargetReceptor tyrosine-protein kinase erbB-2 [1-775,'YVMA',776-1255](Human)
Korea Reserarch Institute of Chemical Technology

US Patent
LigandPNGBDBM700974(N-(5-amino-4-methoxy-2- (methyl(2- morpholinoethyl...)
Affinity DataIC50: 1nMAssay Description:The activity of the compounds of the present invention against HER mutant enzymes was measured using the HTRF system purchased by Cisbio as follows. ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent