BDBM701194 4-[2-(N-(3,3-difluorocyclohexyl)anilino)-2- oxo-ethyl]-1-(indoline-1-carbonyl)piperidine-4- carboxylic acid::US12122750, Example 35B

SMILES O=C(N1CCC(CC(=O)N(c2ccccc2)C2CCCC(F)(F)C2)(C(=O)O)CC1)N1CCc2ccccc21

InChI Key InChIKey=BYWPXSURWIJTOP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 701194   

TargetType-2 angiotensin II receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM701194(4-[2-(N-(3,3-difluorocyclohexyl)anilino)-2- oxo-et...)
Affinity DataKi:  1.03nMAssay Description:Receptor binding affinities (Ki) were determined from a competitive radioligand binding assay with human recombinant ([125I]-Tyr4)-Angiotensin-II (22...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/24/2025
Entry Details
Go to US Patent

TargetType-1 angiotensin II receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM701194(4-[2-(N-(3,3-difluorocyclohexyl)anilino)-2- oxo-et...)
Affinity DataKi:  3.73E+4nMAssay Description:Receptor binding affinities (Ki) were determined from a competitive radioligand binding assay with human recombinant ([125I]-Tyr4)-Angiotensin-II (22...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/24/2025
Entry Details
Go to US Patent