BDBM701257 US12122780, Compound 22

SMILES C[C@@H](c1cccc(-c2ncc(OCC3CCN(C)CC3)cn2)c1)n1c(=O)ccn2c3cc(C#N)ccc3nc12

InChI Key InChIKey=NHUONPIDGBRGNV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 701257   

TargetHepatocyte growth factor receptor(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandPNGBDBM701257(US12122780, Compound 22)
Affinity DataIC50: 11nMAssay Description:The kinase buffer in the kit was used to dilute the enzyme, substrate, ATP and inhibitor.The compound to be tested was diluted 5-fold to the eighth c...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/24/2025
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandPNGBDBM701257(US12122780, Compound 22)
Affinity DataIC50: 76nMAssay Description:The kinase buffer in the kit was used to dilute the enzyme, substrate, ATP and inhibitor.The compound to be tested was diluted 5-fold to the eighth c...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/24/2025
Entry Details
US Patent