BDBM701417 2-(6-Oxo-5-(trifluoromethyl)-1,6-dihydropyridin-3-yl)ethyl (2R,5S)-2,5-dimethyl-4-(5-(trifluoromethyl)pyrimidin-2-yl)piperazine-1-carboxylate::US20240351997, Example 147

SMILES C[C@@H]1CN(c2ncc(C(F)(F)F)cn2)[C@@H](C)CN1C(=O)OCCc1c[nH]c(=O)c(C(F)(F)F)c1

InChI Key InChIKey=GPKMQCRVHVYTMK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 701417   

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Shanghai Qilu Pharmaceutical Research And Development Centre

US Patent
LigandPNGBDBM701417(2-(6-Oxo-5-(trifluoromethyl)-1,6-dihydropyridin-3-...)
Affinity DataIC50: 0.740nMAssay Description:1. Preparation of 384-well histone-coated plate: 25 μL of histone solution was added to each well, and the plate was incubated overnight at 4° C...More data for this Ligand-Target Pair
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Date in BDB:
3/2/2025
Entry Details
US Patent