BDBM702013 US20240360091, Compound (10131)S

SMILES NC(=O)Nc1ccc(OC[C@@H](O)CN2CCN(c3ccc(Cl)c(Cl)c3)CC2)cc1

InChI Key InChIKey=XGEAVIAZYCTOFV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 702013   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702013(US20240360091, Compound (10131)S)
Affinity DataIC50: 103nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702013(US20240360091, Compound (10131)S)
Affinity DataIC50: 947nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent