BDBM702020 US20240360091, Compound (10222)R

SMILES CCc1ccc(N2CCN(C[C@@H](O)COc3ccc(NC(N)=O)cc3)CC2)cc1

InChI Key InChIKey=KWXGEUXJQVRHGK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 702020   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702020(US20240360091, Compound (10222)R)
Affinity DataIC50: 52nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702020(US20240360091, Compound (10222)R)
Affinity DataIC50: 183nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent